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Complement factor H inhibits endothelial cell migration through suppression of STAT3 signaling

Complement factor H (CFH), a major soluble inhibitor of complement, is a plasma protein that directly interacts with the endothelium of blood vessels. Mutations in the CFH gene lead to diseases associated with excessive angiogenesis; however, the underlying mechanisms are unknown. The present study...

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Detalles Bibliográficos
Autores principales: Li, Jiang, Huang, Hong, Xu, Shanhu, Fan, Mengge, Wang, Kaili, Wang, Xia, Zhang, Jiao, Huang, Shengshi, Gatt, Alex, Liu, Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375431/
https://www.ncbi.nlm.nih.gov/pubmed/37522066
http://dx.doi.org/10.3892/etm.2023.12107