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A humanized [Formula: see text] integrin knockin mouse reveals localized intra- and extravascular neutrophil integrin activation in vivo

[Formula: see text] integrins are leukocyte-specific adhesion molecules that are essential for leukocyte recruitment. The lack of tools for reporting [Formula: see text] integrin activation in mice hindered the study of [Formula: see text] integrin-related immune responses in vivo. Here, we generate...

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Detalles Bibliográficos
Autores principales: Wen, Lai, Marki, Alex, Wang, Zhihao, Orecchioni, Marco, Makings, Jeffrey, Billitti, Monica, Wang, Erpei, Suthahar, Sujit S.A., Kim, Kenneth, Kiosses, William B., Mikulski, Zbigniew, Ley, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375464/
https://www.ncbi.nlm.nih.gov/pubmed/35649374
http://dx.doi.org/10.1016/j.celrep.2022.110876