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Development of a novel humanized mouse model to study bronchopulmonary dysplasia

RATIONALE: The role of circulating fetal monocytes in bronchopulmonary dysplasia is not known. We utilized a humanized mouse model that supports human progenitor cell engraftment (MISTRG) to test the hypothesis that prenatal monocyte programming alters early lung development and response to hyperoxi...

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Detalles Bibliográficos
Autores principales: Birkett, Rob, Newar, Janu, Sharma, Abhineet M., Lin, Erika, Blank, Lillian, Swaminathan, Suchitra, Misharin, Alexander, Mestan, Karen K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375491/
https://www.ncbi.nlm.nih.gov/pubmed/37520051
http://dx.doi.org/10.3389/fped.2023.1146014