Cargando…

Small-Molecule Organocatalysis Facilitates In Situ Nucleotide Activation and RNA Copying

[Image: see text] A key challenge in origin-of-life research is the identification of plausible conditions that facilitate multiple steps along the pathway from chemistry to biology. The incompatibility of nucleotide activation chemistry and nonenzymatic template-directed RNA copying has hindered at...

Descripción completa

Detalles Bibliográficos
Autores principales: Aitken, Harry R. M., Wright, Tom H., Radakovic, Aleksandar, Szostak, Jack W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375519/
https://www.ncbi.nlm.nih.gov/pubmed/37431761
http://dx.doi.org/10.1021/jacs.3c04635