Electrostatic Ratchet for Successive Peptide Synthesis in Nonribosomal Molecular Machine RimK

[Image: see text] A nonribosomal peptide-synthesizing molecular machine, RimK, adds l-glutamic acids to the C-terminus of ribosomal protein S6 (RpsF) in vivo and synthesizes poly-α-glutamates in vitro. However, the mechanism of the successive glutamate addition, which is fueled by ATP, remains uncle...

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Detalles Bibliográficos
Autores principales: Ohnuki, Jun, Arimura, Yasuhiro, Kono, Tomonori, Kino, Kuniki, Kurumizaka, Hitoshi, Takano, Mitsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375531/
https://www.ncbi.nlm.nih.gov/pubmed/37452763
http://dx.doi.org/10.1021/jacs.3c03926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375531/
https://www.ncbi.nlm.nih.gov/pubmed/37452763
http://dx.doi.org/10.1021/jacs.3c03926

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