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Electrostatic Ratchet for Successive Peptide Synthesis in Nonribosomal Molecular Machine RimK
[Image: see text] A nonribosomal peptide-synthesizing molecular machine, RimK, adds l-glutamic acids to the C-terminus of ribosomal protein S6 (RpsF) in vivo and synthesizes poly-α-glutamates in vitro. However, the mechanism of the successive glutamate addition, which is fueled by ATP, remains uncle...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375531/ https://www.ncbi.nlm.nih.gov/pubmed/37452763 http://dx.doi.org/10.1021/jacs.3c03926 |