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Triplet-Encoded Prebiotic RNA Aminoacylation

[Image: see text] The encoding step of translation involves attachment of amino acids to cognate tRNAs by aminoacyl-tRNA synthetases, themselves the product of coded peptide synthesis. So, the question arises—before these enzymes evolved, how were primordial tRNAs selectively aminoacylated? Here, we...

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Detalles Bibliográficos
Autores principales: Su, Meng, Schmitt, Christian, Liu, Ziwei, Roberts, Samuel J., Liu, Kim C., Röder, Konstantin, Jäschke, Andres, Wales, David J., Sutherland, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375532/
https://www.ncbi.nlm.nih.gov/pubmed/37435826
http://dx.doi.org/10.1021/jacs.3c03931