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Triplet-Encoded Prebiotic RNA Aminoacylation
[Image: see text] The encoding step of translation involves attachment of amino acids to cognate tRNAs by aminoacyl-tRNA synthetases, themselves the product of coded peptide synthesis. So, the question arises—before these enzymes evolved, how were primordial tRNAs selectively aminoacylated? Here, we...
Autores principales: | Su, Meng, Schmitt, Christian, Liu, Ziwei, Roberts, Samuel J., Liu, Kim C., Röder, Konstantin, Jäschke, Andres, Wales, David J., Sutherland, John D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375532/ https://www.ncbi.nlm.nih.gov/pubmed/37435826 http://dx.doi.org/10.1021/jacs.3c03931 |
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