Super-enhancers complexes zoom in transcription in cancer

Super-enhancers (SEs) consist of multiple typical enhancers enriched at high density with transcription factors, histone-modifying enzymes and cofactors. Oncogenic SEs promote tumorigenesis and malignancy by altering protein-coding gene expression and noncoding regulatory element function. Therefore...

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Detalles Bibliográficos
Autores principales: Wang, MengTing, Chen, QingYang, Wang, ShuJie, Xie, Han, Liu, Jun, Huang, RuiXiang, Xiang, YuFei, Jiang, YanYi, Tian, DaSheng, Bian, ErBao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375641/
https://www.ncbi.nlm.nih.gov/pubmed/37501079
http://dx.doi.org/10.1186/s13046-023-02763-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375641/
https://www.ncbi.nlm.nih.gov/pubmed/37501079
http://dx.doi.org/10.1186/s13046-023-02763-5

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