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A stochastic B cell affinity maturation model to characterize mechanisms of protection for tetravalent dengue vaccine constructs

Dengue annually infects millions of people from a regionally and seasonally varying dengue virus population circulating as four distinct serotypes. Effective protection against dengue infection and disease requires tetravalent vaccine formulations to stimulate a balanced protective immune response t...

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Detalles Bibliográficos
Autores principales: Pannala, Venkat R., Nguyen, Hung D., Wallqvist, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375700/
https://www.ncbi.nlm.nih.gov/pubmed/37520320
http://dx.doi.org/10.3389/fmolb.2023.1100434