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A stochastic B cell affinity maturation model to characterize mechanisms of protection for tetravalent dengue vaccine constructs
Dengue annually infects millions of people from a regionally and seasonally varying dengue virus population circulating as four distinct serotypes. Effective protection against dengue infection and disease requires tetravalent vaccine formulations to stimulate a balanced protective immune response t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375700/ https://www.ncbi.nlm.nih.gov/pubmed/37520320 http://dx.doi.org/10.3389/fmolb.2023.1100434 |