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Smooth muscle dysfunction in the pre-inflammation site in stenotic Crohn’s-like colitis: implication of mechanical stress in bowel dysfunction in gut inflammation

Background and Aims: Gut smooth muscle dysfunctions contribute to symptoms such as abdominal cramping, diarrhea, and constipation in inflammatory bowel disease (IBD). The mechanisms for muscle dysfunctions are incompletely understood. We tested the hypothesis that mechanical stress plays a role in m...

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Detalles Bibliográficos
Autores principales: Johnson, John C., Geesala, Ramasatyaveni, Zhang, Ke, Lin, You-Min, M’Koma, Amosy E., Shi, Xuan-Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375711/
https://www.ncbi.nlm.nih.gov/pubmed/37520831
http://dx.doi.org/10.3389/fphys.2023.1215900