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Restoration of dysregulated intestinal barrier and inflammatory regulation through synergistically ameliorating hypoxia and scavenging reactive oxygen species using ceria nanozymes in ulcerative colitis
BACKGROUND: Reactive oxygen species (ROS) overproduction and excessive hypoxia play pivotal roles in the initiation and progression of ulcerative colitis (UC). Synergistic ROS scavenging and generating O(2) could be a promising strategy for UC treatment. METHODS: Ceria nanozymes (PEG-CNPs) are fabri...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375752/ https://www.ncbi.nlm.nih.gov/pubmed/37507801 http://dx.doi.org/10.1186/s40824-023-00412-8 |