Restoration of dysregulated intestinal barrier and inflammatory regulation through synergistically ameliorating hypoxia and scavenging reactive oxygen species using ceria nanozymes in ulcerative colitis

BACKGROUND: Reactive oxygen species (ROS) overproduction and excessive hypoxia play pivotal roles in the initiation and progression of ulcerative colitis (UC). Synergistic ROS scavenging and generating O(2) could be a promising strategy for UC treatment. METHODS: Ceria nanozymes (PEG-CNPs) are fabri...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Lei, Hengyu, Wang, Pengchong, Zhou, Qinyuan, Yu, Jie, Leng, Xue, Ma, Ruirui, Wang, Danyang, Dong, Kai, Xing, Jianfeng, Dong, Yalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375752/
https://www.ncbi.nlm.nih.gov/pubmed/37507801
http://dx.doi.org/10.1186/s40824-023-00412-8

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