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Upregulation of EphA4 deteriorate brain damage by shifting microglia M1-polarization via NF-κB signaling after focal cerebral ischemia in rats

Ischemic stroke is the main reason of disability and mortality in many countries, and currently has limited treatments. The post-stroke inflammation characterized with microglia activation and polarization has been regarded as a promising therapeutic target for ischemic stroke. After ischemia, the a...

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Detalles Bibliográficos
Autores principales: Wei, Hui-Xing, Guan, Yun-Ni, Chen, Ping-Ping, Rao, Zhao-Zeng, Yang, Jin-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375859/
https://www.ncbi.nlm.nih.gov/pubmed/37519758
http://dx.doi.org/10.1016/j.heliyon.2023.e18429