A Novel ENU-Induced Mfn2 Mutation Causes Motor Deficits in Mice without Causing Peripheral Neuropathy

SIMPLE SUMMARY: The fission and fusion of mitochondria are important processes for maintaining mitochondrial health. One of the proteins responsible for mediating mitochondrial fusion, mitofusin 2 (MFN2), has over 100 known mutations that cause Charcot–Marie–Tooth disease type 2A (CMT2A). This disea...

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Detalles Bibliográficos
Autores principales: Hines, Timothy J., Bailey, Janice, Liu, Hedi, Guntur, Anyonya R., Seburn, Kevin L., Pratt, Samia L., Funke, Jonathan R., Tarantino, Lisa M., Burgess, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376023/
https://www.ncbi.nlm.nih.gov/pubmed/37508383
http://dx.doi.org/10.3390/biology12070953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376023/
https://www.ncbi.nlm.nih.gov/pubmed/37508383
http://dx.doi.org/10.3390/biology12070953

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