ABC Transporter C1 Prevents Dimethyl Fumarate from Targeting Alzheimer’s Disease

SIMPLE SUMMARY: Reusing drugs could potentially shorten the development time for the effective treatment of dementia. Here, we tested a drug—dimethyl fumarate—for its efficacy in reducing Alzheimer’s disease-related changes in the brain. We discovered that the drug is not efficient due to the involv...

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Detalles Bibliográficos
Autores principales: Möhle, Luisa, Stefan, Katja, Bascuñana, Pablo, Brackhan, Mirjam, Brüning, Thomas, Eiriz, Ivan, El Menuawy, Ahmed, van Genderen, Sylvie, Santos-García, Irene, Górska, Anna Maria, Villa, María, Wu, Jingyun, Stefan, Sven Marcel, Pahnke, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376064/
https://www.ncbi.nlm.nih.gov/pubmed/37508364
http://dx.doi.org/10.3390/biology12070932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376064/
https://www.ncbi.nlm.nih.gov/pubmed/37508364
http://dx.doi.org/10.3390/biology12070932

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