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ABC Transporter C1 Prevents Dimethyl Fumarate from Targeting Alzheimer’s Disease
SIMPLE SUMMARY: Reusing drugs could potentially shorten the development time for the effective treatment of dementia. Here, we tested a drug—dimethyl fumarate—for its efficacy in reducing Alzheimer’s disease-related changes in the brain. We discovered that the drug is not efficient due to the involv...
Autores principales: | Möhle, Luisa, Stefan, Katja, Bascuñana, Pablo, Brackhan, Mirjam, Brüning, Thomas, Eiriz, Ivan, El Menuawy, Ahmed, van Genderen, Sylvie, Santos-García, Irene, Górska, Anna Maria, Villa, María, Wu, Jingyun, Stefan, Sven Marcel, Pahnke, Jens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376064/ https://www.ncbi.nlm.nih.gov/pubmed/37508364 http://dx.doi.org/10.3390/biology12070932 |
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