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Cocaine Regulates NLRP3 Inflammasome Activity and CRF Signaling in a Region- and Sex-Dependent Manner in Rat Brain

Cocaine, one of the most abused drugs worldwide, is capable of activating microglia in vitro and in vivo. Several neuroimmune pathways have been suggested to play roles in cocaine-mediated microglial activation. Previous work showed that cocaine activates microglia in a region-specific manner in the...

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Detalles Bibliográficos
Autores principales: Cheng, Yan, Dempsey, Rachael Elizabeth, Roodsari, Soheil Kazemi, Shuboni-Mulligan, Dorela D., George, Olivier, Sanford, Larry D., Guo, Ming-Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376186/
https://www.ncbi.nlm.nih.gov/pubmed/37509440
http://dx.doi.org/10.3390/biomedicines11071800