Manoalide Induces Intrinsic Apoptosis by Oxidative Stress and Mitochondrial Dysfunction in Human Osteosarcoma Cells

Osteosarcoma (OS) is the most common primary malignant bone tumor that produces immature osteoid. Metastatic OS has a poor prognosis with a death rate of >70%. Manoalide is a natural sesterterpenoid isolated from marine sponges. It is a phospholipase A2 inhibitor with anti-inflammatory, analgesic...

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Detalles Bibliográficos
Autores principales: Yao, Zhi-Kang, Jean, Yen-Hsuan, Lin, Sung-Chun, Lai, Yu-Cheng, Chen, Nan-Fu, Tseng, Chung-Chih, Chen, Wu-Fu, Wen, Zhi-Hong, Kuo, Hsiao-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376204/
https://www.ncbi.nlm.nih.gov/pubmed/37507960
http://dx.doi.org/10.3390/antiox12071422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376204/
https://www.ncbi.nlm.nih.gov/pubmed/37507960
http://dx.doi.org/10.3390/antiox12071422

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