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Colorectal Cancer Cell Invasion and Functional Properties Depend on Peri-Tumoral Extracellular Matrix

We investigated how the extracellular matrix (ECM) affects LoVo colorectal cancer cells behavior during a spatiotemporal invasion. Epithelial-to-mesenchymal transition (EMT) markers, matrix-degrading enzymes, and morphological phenotypes expressed by LoVo-S (doxorubicin-sensitive) and higher aggress...

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Detalles Bibliográficos
Autores principales: Franchi, Marco, Karamanos, Konstantinos-Athanasios, Cappadone, Concettina, Calonghi, Natalia, Greco, Nicola, Franchi, Leonardo, Onisto, Maurizio, Masola, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376217/
https://www.ncbi.nlm.nih.gov/pubmed/37509428
http://dx.doi.org/10.3390/biomedicines11071788