Modeling Cardiotoxicity in Pediatric Oncology Patients Using Patient-Specific iPSC-Derived Cardiomyocytes Reveals Downregulation of Cardioprotective microRNAs

Anthracyclines are widely used in the treatment of many solid cancers, but their efficacy is limited by cardiotoxicity. As the number of pediatric cancer survivors continues to rise, there has been a concomitant increase in people living with anthracycline-induced cardiotoxicity. Accordingly, there...

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Detalles Bibliográficos
Autores principales: Reinal, Ignacio, Ontoria-Oviedo, Imelda, Selva, Marta, Casini, Marilù, Peiró-Molina, Esteban, Fambuena-Santos, Carlos, Climent, Andreu M., Balaguer, Julia, Cañete, Adela, Mora, Jaume, Raya, Ángel, Sepúlveda, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376252/
https://www.ncbi.nlm.nih.gov/pubmed/37507917
http://dx.doi.org/10.3390/antiox12071378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376252/
https://www.ncbi.nlm.nih.gov/pubmed/37507917
http://dx.doi.org/10.3390/antiox12071378

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