Human NCF1(90H) Variant Promotes IL-23/IL-17—Dependent Mannan-Induced Psoriasis and Psoriatic Arthritis

Recently, a major single nucleotide variant on the NCF1 gene, leading to an amino acid replacement from arginine to histidine at position 90 (NCF1(R90H)), associated with low production of reactive oxygen species (ROS), was found to be causative for several autoimmune diseases. Psoriasis in the skin...

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Detalles Bibliográficos
Autores principales: Li, Yanpeng, Li, Zhilei, Nandakumar, Kutty Selva, Holmdahl, Rikard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376330/
https://www.ncbi.nlm.nih.gov/pubmed/37507888
http://dx.doi.org/10.3390/antiox12071348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376330/
https://www.ncbi.nlm.nih.gov/pubmed/37507888
http://dx.doi.org/10.3390/antiox12071348

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