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Human NCF1(90H) Variant Promotes IL-23/IL-17—Dependent Mannan-Induced Psoriasis and Psoriatic Arthritis
Recently, a major single nucleotide variant on the NCF1 gene, leading to an amino acid replacement from arginine to histidine at position 90 (NCF1(R90H)), associated with low production of reactive oxygen species (ROS), was found to be causative for several autoimmune diseases. Psoriasis in the skin...
Autores principales: | Li, Yanpeng, Li, Zhilei, Nandakumar, Kutty Selva, Holmdahl, Rikard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376330/ https://www.ncbi.nlm.nih.gov/pubmed/37507888 http://dx.doi.org/10.3390/antiox12071348 |
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