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Molecular Anatomy of the Class I Ligase Ribozyme for Elucidation of the Activity-Generating Unit

SIMPLE SUMMARY: The class I ligase is an in-vitro-evolved ribozyme with a high catalytic turnover. In the present study, we considered the conditions under which this ribozyme retains ligation activity by removing the partial structure and by splitting. The ligation activity was maintained even when...

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Detalles Bibliográficos
Autores principales: Kasuga, Miho, Mutsuro-Aoki, Hiromi, Ando, Tadashi, Tamura, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376402/
https://www.ncbi.nlm.nih.gov/pubmed/37508441
http://dx.doi.org/10.3390/biology12071012