Pharmacological and Genetic Suppression of VDAC1 Alleviates the Development of Mitochondrial Dysfunction in Endothelial and Fibroblast Cell Cultures upon Hyperglycemic Conditions

Prolonged hyperglycemia related to diabetes and its complications leads to multiple cellular disorders, the central one being the dysfunction of mitochondria. Voltage-dependent anion channels (VDAC) of the outer mitochondrial membrane control the metabolic, ionic, and energy cross-talk between mitoc...

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Detalles Bibliográficos
Autores principales: Belosludtsev, Konstantin N., Serov, Dmitriy A., Ilzorkina, Anna I., Starinets, Vlada S., Dubinin, Mikhail V., Talanov, Eugeny Yu., Karagyaur, Maxim N., Primak, Alexandra L., Belosludtseva, Natalia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376467/
https://www.ncbi.nlm.nih.gov/pubmed/37507997
http://dx.doi.org/10.3390/antiox12071459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376467/
https://www.ncbi.nlm.nih.gov/pubmed/37507997
http://dx.doi.org/10.3390/antiox12071459

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