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Pharmacological and Genetic Suppression of VDAC1 Alleviates the Development of Mitochondrial Dysfunction in Endothelial and Fibroblast Cell Cultures upon Hyperglycemic Conditions
Prolonged hyperglycemia related to diabetes and its complications leads to multiple cellular disorders, the central one being the dysfunction of mitochondria. Voltage-dependent anion channels (VDAC) of the outer mitochondrial membrane control the metabolic, ionic, and energy cross-talk between mitoc...
Autores principales: | Belosludtsev, Konstantin N., Serov, Dmitriy A., Ilzorkina, Anna I., Starinets, Vlada S., Dubinin, Mikhail V., Talanov, Eugeny Yu., Karagyaur, Maxim N., Primak, Alexandra L., Belosludtseva, Natalia V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376467/ https://www.ncbi.nlm.nih.gov/pubmed/37507997 http://dx.doi.org/10.3390/antiox12071459 |
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