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Simulation of Vancomycin Exposure Using Trough and Peak Levels Achieves the Target Area under the Steady-State Concentration–Time Curve in ICU Patients

The therapeutic drug monitoring (TDM) of vancomycin (VCM) in critically ill patients often results in the estimated area being under the concentration–time curve (AUC) values that deviate from individual observations. In this study, we investigated the factors influencing the achievement of the targ...

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Detalles Bibliográficos
Autores principales: Ibe, Yuta, Ishigo, Tomoyuki, Fujii, Satoshi, Takahashi, Satoshi, Fukudo, Masahide, Sato, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376485/
https://www.ncbi.nlm.nih.gov/pubmed/37508208
http://dx.doi.org/10.3390/antibiotics12071113