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Simulation of Vancomycin Exposure Using Trough and Peak Levels Achieves the Target Area under the Steady-State Concentration–Time Curve in ICU Patients
The therapeutic drug monitoring (TDM) of vancomycin (VCM) in critically ill patients often results in the estimated area being under the concentration–time curve (AUC) values that deviate from individual observations. In this study, we investigated the factors influencing the achievement of the targ...
Autores principales: | Ibe, Yuta, Ishigo, Tomoyuki, Fujii, Satoshi, Takahashi, Satoshi, Fukudo, Masahide, Sato, Hideki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376485/ https://www.ncbi.nlm.nih.gov/pubmed/37508208 http://dx.doi.org/10.3390/antibiotics12071113 |
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