Teneligliptin Co-Infusion Alleviates Morphine Tolerance by Inhibition of Spinal Microglial Cell Activation in Streptozotocin-Induced Diabetic Rats

Morphine (MOR) is a commonly prescribed drug for the treatment of moderate to severe diabetic neuropathic pain (DNP). However, long-term MOR treatment is limited by morphine analgesic tolerance (MAT). The activation of microglial cells and the release of glia-derived proinflammatory cytokines are kn...

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Detalles Bibliográficos
Autores principales: Kuthati, Yaswanth, Rao, Vaikar Navakanth, Huang, Wei-Hsiu, Busa, Prabhakar, Wong, Chih-Shung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376493/
https://www.ncbi.nlm.nih.gov/pubmed/37508016
http://dx.doi.org/10.3390/antiox12071478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376493/
https://www.ncbi.nlm.nih.gov/pubmed/37508016
http://dx.doi.org/10.3390/antiox12071478

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