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Teneligliptin Co-Infusion Alleviates Morphine Tolerance by Inhibition of Spinal Microglial Cell Activation in Streptozotocin-Induced Diabetic Rats
Morphine (MOR) is a commonly prescribed drug for the treatment of moderate to severe diabetic neuropathic pain (DNP). However, long-term MOR treatment is limited by morphine analgesic tolerance (MAT). The activation of microglial cells and the release of glia-derived proinflammatory cytokines are kn...
Autores principales: | Kuthati, Yaswanth, Rao, Vaikar Navakanth, Huang, Wei-Hsiu, Busa, Prabhakar, Wong, Chih-Shung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376493/ https://www.ncbi.nlm.nih.gov/pubmed/37508016 http://dx.doi.org/10.3390/antiox12071478 |
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