Long-Term Use of Amoxicillin Is Associated with Changes in Gene Expression and DNA Methylation in Patients with Low Back Pain and Modic Changes

Long-term antibiotics are prescribed for a variety of medical conditions, recently including low back pain with Modic changes. The molecular impact of such treatment is unknown. We conducted longitudinal transcriptome and epigenome analyses in patients (n = 100) receiving amoxicillin treatment or pl...

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Detalles Bibliográficos
Autores principales: Vigeland, Maria Dehli, Flåm, Siri Tennebø, Vigeland, Magnus Dehli, Espeland, Ansgar, Zucknick, Manuela, Wigemyr, Monica, Bråten, Lars Christian Haugli, Gjefsen, Elisabeth, Zwart, John-Anker, Storheim, Kjersti, Pedersen, Linda Margareth, Selmer, Kaja, Lie, Benedicte Alexandra, Gervin, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376514/
https://www.ncbi.nlm.nih.gov/pubmed/37508313
http://dx.doi.org/10.3390/antibiotics12071217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376514/
https://www.ncbi.nlm.nih.gov/pubmed/37508313
http://dx.doi.org/10.3390/antibiotics12071217

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