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Hyperforin Enhances Heme Oxygenase-1 Expression Triggering Lipid Peroxidation in BRAF-Mutated Melanoma Cells and Hampers the Expression of Pro-Metastatic Markers

Hyperforin (HPF) is an acylphloroglucinol compound found abundantly in Hypericum perforatum extract which exhibits antidepressant, anti-inflammatory, antimicrobial, and antitumor activities. Our recent study revealed a potent antimelanoma effect of HPF, which hinders melanoma cell proliferation, mot...

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Detalles Bibliográficos
Autores principales: Cardile, Alessia, Passarini, Carlotta, Zanrè, Valentina, Fiore, Alessandra, Menegazzi, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376533/
https://www.ncbi.nlm.nih.gov/pubmed/37507910
http://dx.doi.org/10.3390/antiox12071369