Cargando…
Hyperforin Enhances Heme Oxygenase-1 Expression Triggering Lipid Peroxidation in BRAF-Mutated Melanoma Cells and Hampers the Expression of Pro-Metastatic Markers
Hyperforin (HPF) is an acylphloroglucinol compound found abundantly in Hypericum perforatum extract which exhibits antidepressant, anti-inflammatory, antimicrobial, and antitumor activities. Our recent study revealed a potent antimelanoma effect of HPF, which hinders melanoma cell proliferation, mot...
Autores principales: | Cardile, Alessia, Passarini, Carlotta, Zanrè, Valentina, Fiore, Alessandra, Menegazzi, Marta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376533/ https://www.ncbi.nlm.nih.gov/pubmed/37507910 http://dx.doi.org/10.3390/antiox12071369 |
Ejemplares similares
-
Hyperforin Elicits Cytostatic/Cytotoxic Activity in Human Melanoma Cell Lines, Inhibiting Pro-Survival NF-κB, STAT3, AP1 Transcription Factors and the Expression of Functional Proteins Involved in Mitochondrial and Cytosolic Metabolism
por: Cardile, Alessia, et al.
Publicado: (2023) -
Salviolone from Salvia miltiorrhiza Roots Impairs Cell Cycle Progression, Colony Formation, and Metalloproteinase-2 Activity in A375 Melanoma Cells: Involvement of P21(Cip1/Waf1) Expression and STAT3 Phosphorylation
por: Zanrè, Valentina, et al.
Publicado: (2022) -
The Expression of Heme Oxygenase-1 Induced by Lansoprazole
por: Takagi, Tomohisa, et al.
Publicado: (2009) -
Anti-Tumor Activity of Hypericum perforatum L. and Hyperforin through Modulation of Inflammatory Signaling, ROS Generation and Proton Dynamics
por: Menegazzi, Marta, et al.
Publicado: (2020) -
Upregulation of miR-34a-5p, miR-20a-3p and miR-29a-3p by Onconase in A375 Melanoma Cells Correlates with the Downregulation of Specific Onco-Proteins
por: De Tomi, Elisa, et al.
Publicado: (2022)