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Interactions between Angiotensin Type-1 Antagonists, Statins, and ROCK Inhibitors in a Rat Model of L-DOPA-Induced Dyskinesia

Statins have been proposed for L-DOPA-induced dyskinesia (LID) treatment. Statin anti-dyskinetic effects were related to the inhibition of the Ras-ERK pathway. However, the mechanisms responsible for the anti-LID effect are unclear. Changes in cholesterol homeostasis and oxidative stress- and inflam...

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Detalles Bibliográficos
Autores principales: Lopez-Lopez, Andrea, Valenzuela, Rita, Rodriguez-Perez, Ana Isabel, Guerra, María J., Labandeira-Garcia, Jose Luis, Muñoz, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376833/
https://www.ncbi.nlm.nih.gov/pubmed/37507992
http://dx.doi.org/10.3390/antiox12071454