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Discovery of Novel Myristic Acid Derivatives as N-Myristoyltransferase Inhibitors: Design, Synthesis, Analysis, Computational Studies and Antifungal Activity

In recent years, N-Myristoyltransferase (NMT) has been identified as a new target for the treatment of fungal infections. It is observed that at present, there are increased rates of morbidity and mortality due to fungal infections. Hence, a series of novel myristic acid derivatives were designed vi...

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Detalles Bibliográficos
Autores principales: Javid, Saleem, Ather, Hissana, Hani, Umme, Siddiqua, Ayesha, Asif Ansari, Shaik Mohammad, Shanmugarajan, Dhivya, Yogish Kumar, Honnavalli, Arivuselvam, Rajaguru, Purohit, Madhusudan N., Kumar, B. R. Prashantha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376843/
https://www.ncbi.nlm.nih.gov/pubmed/37508263
http://dx.doi.org/10.3390/antibiotics12071167