Perfusion of MC3T3E1 Preosteoblast Spheroids within Polysaccharide-Based Hydrogel Scaffolds: An Experimental and Numerical Study at the Bioreactor Scale

The traditional 3D culture systems in vitro lack the biological and mechanical spatiotemporal stimuli characteristic to native tissue development. In our study, we combined porous polysaccharide-based hydrogel scaffolds with a bioreactor-type perfusion device that generates favorable mechanical stre...

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Detalles Bibliográficos
Autores principales: Grenier, Jérôme, David, Bertrand, Journé, Clément, Cicha, Iwona, Letourneur, Didier, Duval, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376891/
https://www.ncbi.nlm.nih.gov/pubmed/37508876
http://dx.doi.org/10.3390/bioengineering10070849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376891/
https://www.ncbi.nlm.nih.gov/pubmed/37508876
http://dx.doi.org/10.3390/bioengineering10070849

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