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Human Patient-Derived Brain Tumor Models to Recapitulate Ependymoma Tumor Vasculature

Despite in vivo malignancy, ependymoma lacks cell culture models, thus limiting therapy development. Here, we used a tunable three-dimensional (3D) culture system to approximate the ependymoma microenvironment for recapitulating a patient’s tumor in vitro. Our data showed that the inclusion of VEGF...

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Detalles Bibliográficos
Autores principales: Tang-Schomer, Min D., Bookland, Markus J., Sargent, Jack E., N. Jackvony, Taylor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376907/
https://www.ncbi.nlm.nih.gov/pubmed/37508868
http://dx.doi.org/10.3390/bioengineering10070840