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Human Patient-Derived Brain Tumor Models to Recapitulate Ependymoma Tumor Vasculature
Despite in vivo malignancy, ependymoma lacks cell culture models, thus limiting therapy development. Here, we used a tunable three-dimensional (3D) culture system to approximate the ependymoma microenvironment for recapitulating a patient’s tumor in vitro. Our data showed that the inclusion of VEGF...
Autores principales: | Tang-Schomer, Min D., Bookland, Markus J., Sargent, Jack E., N. Jackvony, Taylor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376907/ https://www.ncbi.nlm.nih.gov/pubmed/37508868 http://dx.doi.org/10.3390/bioengineering10070840 |
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