A survey of the specificity and mechanism of 1,6 hexanediol-induced disruption of nuclear transport

Selective transport through the nuclear pore complex (NPC) depends on the dynamic binding of FG-repeat containing nucleoporins, the FG-nups, with each other and with Karyopherins (Kaps). Here, we assessed the specificity and mechanism by which the aliphatic alcohol 1,6-hexanediol (1,6HD) disrupts th...

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Detalles Bibliográficos
Autores principales: Barrientos, Elizabeth C. Riquelme, Otto, Tegan A., Mouton, Sara N., Steen, Anton, Veenhoff, Liesbeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376917/
https://www.ncbi.nlm.nih.gov/pubmed/37498221
http://dx.doi.org/10.1080/19491034.2023.2240139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376917/
https://www.ncbi.nlm.nih.gov/pubmed/37498221
http://dx.doi.org/10.1080/19491034.2023.2240139

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