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Integrative CRISPR Activation and Small Molecule Inhibitor Screening for lncRNA Mediating BRAF Inhibitor Resistance in Melanoma

The incidence of melanoma, being one of the most commonly occurring cancers, has been rising since the past decade. Patients at advanced stages of the disease have very poor prognoses, as opposed to at the earlier stages. The conventional targeted therapy is well defined and effective for advanced-s...

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Detalles Bibliográficos
Autores principales: Shamloo, Sama, Kloetgen, Andreas, Petroulia, Stavroula, Hockemeyer, Kathryn, Sievers, Sonja, Tsirigos, Aristotelis, Aifantis, Ioannis, Imig, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377043/
https://www.ncbi.nlm.nih.gov/pubmed/37509693
http://dx.doi.org/10.3390/biomedicines11072054