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Senescence-Driven Inflammatory and Trophic Microenvironment Imprints Mesenchymal Stromal/Stem Cells in Osteoarthritic Patients

Senescent cells promote progressive tissue degeneration through the establishment of a combined inflammatory and trophic microenvironment. The cellular senescence state has therefore emerged as a central driving mechanism of numerous age-related diseases, including osteoarthritis (OA), the most comm...

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Detalles Bibliográficos
Autores principales: Fusi, Giuseppe, Constantinides, Michael, Fissoun, Christina, Pichard, Lydiane, Pers, Yves-Marie, Ferreira-Lopez, Rosanna, Pantesco, Veronique, Poulet, Christophe, Malaise, Olivier, De Seny, Dominique, Lemaitre, Jean-Marc, Jorgensen, Christian, Brondello, Jean-Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377055/
https://www.ncbi.nlm.nih.gov/pubmed/37509633
http://dx.doi.org/10.3390/biomedicines11071994