Cargando…
Senescence-Driven Inflammatory and Trophic Microenvironment Imprints Mesenchymal Stromal/Stem Cells in Osteoarthritic Patients
Senescent cells promote progressive tissue degeneration through the establishment of a combined inflammatory and trophic microenvironment. The cellular senescence state has therefore emerged as a central driving mechanism of numerous age-related diseases, including osteoarthritis (OA), the most comm...
Autores principales: | Fusi, Giuseppe, Constantinides, Michael, Fissoun, Christina, Pichard, Lydiane, Pers, Yves-Marie, Ferreira-Lopez, Rosanna, Pantesco, Veronique, Poulet, Christophe, Malaise, Olivier, De Seny, Dominique, Lemaitre, Jean-Marc, Jorgensen, Christian, Brondello, Jean-Marc |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377055/ https://www.ncbi.nlm.nih.gov/pubmed/37509633 http://dx.doi.org/10.3390/biomedicines11071994 |
Ejemplares similares
-
Influence of Glucocorticoids on Cellular Senescence Hallmarks in Osteoarthritic Fibroblast-like Synoviocytes
por: Malaise, Olivier, et al.
Publicado: (2021) -
Mesenchymal stem cell senescence alleviates their intrinsic and seno-suppressive paracrine properties contributing to osteoarthritis development
por: Malaise, Olivier, et al.
Publicado: (2019) -
CEMIP (KIAA1199) induces a fibrosis-like process in osteoarthritic chondrocytes
por: Deroyer, Céline, et al.
Publicado: (2019) -
Cellular Senescence is a Common Characteristic Shared by Preneoplasic and Osteo-Arthritic Tissue
por: Brondello, Jean-Marc, et al.
Publicado: (2010) -
Cellular senescence impact on immune cell fate and function
por: Vicente, Rita, et al.
Publicado: (2016)