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Pro-Calcifying Role of Enzymatically Modified LDL (eLDL) in Aortic Valve Sclerosis via Induction of IL-6 and IL-33

One of the contributors to atherogenesis is enzymatically modified LDL (eLDL). eLDL was detected in all stages of aortic valve sclerosis and was demonstrated to trigger the activation of p38 mitogen-activated protein kinase (p38 MAPK), which has been identified as a pro-inflammatory protein in ather...

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Detalles Bibliográficos
Autores principales: Witz, Annemarie, Effertz, Denise, Goebel, Nora, Schwab, Matthias, Franke, Ulrich F. W., Torzewski, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377083/
https://www.ncbi.nlm.nih.gov/pubmed/37509127
http://dx.doi.org/10.3390/biom13071091