Yeast Models of Amyotrophic Lateral Sclerosis Type 8 Mimic Phenotypes Seen in Mammalian Cells Expressing Mutant VAPB(P56S)

Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disease that results in the loss of motor neurons and can occur sporadically or due to genetic mutations. Among the 30 genes linked to familial ALS, a P56S mutation in VAPB, an ER-resident protein that functions at membrane contact s...

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Detalles Bibliográficos
Autores principales: Stump, AnnaMari L., Rioux, Daniel J., Albright, Richard, Melki, Guiliano L., Prosser, Derek C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377116/
https://www.ncbi.nlm.nih.gov/pubmed/37509182
http://dx.doi.org/10.3390/biom13071147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377116/
https://www.ncbi.nlm.nih.gov/pubmed/37509182
http://dx.doi.org/10.3390/biom13071147

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