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KRAS p.G12C Mutation in Metastatic Colorectal Cancer: Prognostic Implications and Advancements in Targeted Therapies

SIMPLE SUMMARY: In this review, we aim to clarify the prognostic significance of the KRAS p.G12C mutation in metastatic colorectal cancer, emphasizing its potential as a promising therapeutic target. Moreover, our objective is to increase readers’ awareness of the factors that can influence diverse...

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Detalles Bibliográficos
Autores principales: Ottaiano, Alessandro, Sabbatino, Francesco, Perri, Francesco, Cascella, Marco, Sirica, Roberto, Patrone, Renato, Capuozzo, Maurizio, Savarese, Giovanni, Ianniello, Monica, Petrillo, Nadia, Circelli, Luisa, Granata, Vincenza, Berretta, Massimiliano, Santorsola, Mariachiara, Nasti, Guglielmo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377118/
https://www.ncbi.nlm.nih.gov/pubmed/37509241
http://dx.doi.org/10.3390/cancers15143579