Decursinol Angelate Inhibits Glutamate Dehydrogenase 1 Activity and Induces Intrinsic Apoptosis in MDR-CRC Cells

SIMPLE SUMMARY: Upregulated glutaminolysis is a typical hallmark of malignant tumors across different cancers. In our previous published paper, we proved the ability of decursinol angelate (DA) to bind to glutamate dehydrogenase 1 (GDH1) in the abortive complex of the ADP activation site and inhibit...

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Detalles Bibliográficos
Autores principales: Chang, Sukkum Ngullie, Kang, Sun Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377166/
https://www.ncbi.nlm.nih.gov/pubmed/37509203
http://dx.doi.org/10.3390/cancers15143541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377166/
https://www.ncbi.nlm.nih.gov/pubmed/37509203
http://dx.doi.org/10.3390/cancers15143541

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