Cargando…

Dexmedetomidine Improves Anxiety-like Behaviors in Sleep-Deprived Mice by Inhibiting the p38/MSK1/NFκB Pathway and Reducing Inflammation and Oxidative Stress

(1) Background: Sleep deprivation (SD) triggers a range of neuroinflammatory responses. Dexmedetomidine can improve sleep deprivation-induced anxiety by reducing neuroinflammatory response but the mechanism is unclear; (2) Methods: The sleep deprivation model was established by using an interference...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jiangjing, Zhang, Heming, Deng, Bin, Wang, Xin, Liang, Peng, Xu, Shenglong, Jing, Ziwei, Xiao, Zhibin, Sun, Li, Gao, Changjun, Wang, Jin, Sun, Xude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377202/
https://www.ncbi.nlm.nih.gov/pubmed/37508990
http://dx.doi.org/10.3390/brainsci13071058