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Dexmedetomidine Improves Anxiety-like Behaviors in Sleep-Deprived Mice by Inhibiting the p38/MSK1/NFκB Pathway and Reducing Inflammation and Oxidative Stress
(1) Background: Sleep deprivation (SD) triggers a range of neuroinflammatory responses. Dexmedetomidine can improve sleep deprivation-induced anxiety by reducing neuroinflammatory response but the mechanism is unclear; (2) Methods: The sleep deprivation model was established by using an interference...
Autores principales: | Li, Jiangjing, Zhang, Heming, Deng, Bin, Wang, Xin, Liang, Peng, Xu, Shenglong, Jing, Ziwei, Xiao, Zhibin, Sun, Li, Gao, Changjun, Wang, Jin, Sun, Xude |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377202/ https://www.ncbi.nlm.nih.gov/pubmed/37508990 http://dx.doi.org/10.3390/brainsci13071058 |
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