PFKFB3 Inhibitor 3PO Reduces Cardiac Remodeling after Myocardial Infarction by Regulating the TGF-β1/SMAD2/3 Pathway

Adverse cardiac remodeling, including cardiac fibrosis, after myocardial infarction (MI) is a major cause of long-term heart failure. 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3), an enzyme that regulates glucose metabolism, also plays an important role in various fibrotic and card...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Qian, Zong, Xiao, Zhuang, Lingfang, Pan, Roubai, Tudi, Xierenayi, Fan, Qin, Tao, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377206/
https://www.ncbi.nlm.nih.gov/pubmed/37509108
http://dx.doi.org/10.3390/biom13071072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377206/
https://www.ncbi.nlm.nih.gov/pubmed/37509108
http://dx.doi.org/10.3390/biom13071072

Ejemplares similares