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PFKFB3 Inhibitor 3PO Reduces Cardiac Remodeling after Myocardial Infarction by Regulating the TGF-β1/SMAD2/3 Pathway

Adverse cardiac remodeling, including cardiac fibrosis, after myocardial infarction (MI) is a major cause of long-term heart failure. 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3), an enzyme that regulates glucose metabolism, also plays an important role in various fibrotic and card...

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Detalles Bibliográficos
Autores principales:	Yang, Qian, Zong, Xiao, Zhuang, Lingfang, Pan, Roubai, Tudi, Xierenayi, Fan, Qin, Tao, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377206/ https://www.ncbi.nlm.nih.gov/pubmed/37509108 http://dx.doi.org/10.3390/biom13071072

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